Biological databases are centralised resources that contain representations of DNA and protein sequences and their associated information. WHAT ARE THE BIOLOGICAL DATABASES ??? 6.2 Primary sequence databases 6.2.1 Introduction In the early 1980’s, several primary database projects evolved in different parts of the world (see table 6.1). It is an India's Largest Biological WebPortal Created for Providing Free Facilities to Research Scholars, Students, Teachers and Other Who Want to Work with Life Sciences. Various biological databases are available online, which are classified based on various criteria for ease of access and use. What is Primary Data? a) entry. Biological Databases: 1. Primary Databases • They contains biomolecular data in its original form. 3. There are two main classes of databases:DNA (nucleotide) databases and protein databases. Margaret Dayhoff developed the first protein sequence database called. Primary databases contain primary sequence information (nucleotide or protein) and accompanying annotation information regarding function, bibliographies, cross-references to other databases, etc. Each record in a database is called an. c) record. Databases consisting of data derived experimentally such as nucleotide sequences and three dimensional structures are known as primary databases. d) ticket. Primary databases store and make data available to the public, acting as repositories. c) Atlas of protein sequence and structure. 9 10. NK BioSoft Provides Free Life Sciences, Agricultural Sciences Books, Journals, Softwares, Biological Documentries, Biological Calculators, Animated Tutorials and List of Major Biological Search Engines. a) SWISS PROT. Primary data is a type of data that is collected by researchers directly from main sources through interviews, surveys, experiments, etc. EMBnet MCB, feb 2005 An introduction to biological databases Marie-Claude.Blatter@isb-sib.ch EMBnet MCB, feb 2005 What is a database ? • Experimental results are submitted directly into the database by researchers, … b) file. d) Protein sequence databank. • A collection of – structured – searchable (index)-> table of contents – updated periodically (release)-> new edition – cross-referenced (hyperlinks) -> … Databases and Different types of Biological Databases Definition: A collection of related data arranged in a way suitable for adding, locating, removing and modifying the data The database which store biological data is called biological database Eg: nucleotide sequence database Literature databases include. Typesof BiologicalDatabases • On the basis of source: Primary Databases Secondary Databases 7. Biological Databases serve a critical purpose in the collation and organization of data related to biological systems. The primary sequence databases have grown tremendously over the years. Primary data are usually collected from the source—where the data originally originates from and are regarded as the best kind of data in research. 8 9. Secondary Databases: Those data that are derived from the analysis or treatment of primary data such as secondary structures, hydrophobicity plots, and domain are stored in secondary databases DNA (nucleotide) Protein They provide a computational support and a user-friendly interface to a researcher for a meaningful analysis of biological data. 2. Secondary biological databases, however, summarize the results from analyses of primary protein sequence databases. b) PDB. That is collected by researchers directly from main sources through interviews, surveys experiments. 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